Conception, Pregnancy and Child Birth

Draw Attention Towards Mucoadhesive Buccal Drug Delivery System

1. Introduction

Considerable attention has been focused in recent years on the delivery through the oral mucosa of drugs which have a high first pass metabolism (i.e., metabolized to a large extent by the liver during the first pass there through and therefore do not enter the blood stream) or degrade in the gastrointestinal tract. Transmucosal delivery has also been considered for treatment of oral disorders and as a local anesthetic1.

Buccal delivery involves the administration of the desired drug through the buccal mucosal … Continue Reading